Grey's Anatomy Season 18 follows the doctors of Grey Sloan Memorial Hospital as they navigate personal and professional challenges. Dr. Meredith Grey continues balancing her career and family after significant losses, while Dr. Miranda Bailey faces tough decisions as Chief of Surgery. The season introduces new characters like Dr. Jules Millin and Dr. Simone Griffith, bringing fresh dynamics to the hospital. The staff deals with the pressures of healthcare politics, ethical dilemmas, and the lingering effects of the pandemic, all while managing high-stakes medical cases and complex relationships.